I have a 53/39 and 11-32 now. A move to 50/37 and 10-33 would be an improvement and something I’m really considering although it’s a lot of money to switch to AXS. I spin out, or come really close to it, on a good number of descents where I live making most of my intervals hard to complete correctly. Not just z5 and z6 intervals but z2-z4 in some areas are hard to stay in. I live in an area with a lot of rolling hills, nearly impossible to work around useless I repeat a stretch of road a lot which would take away what I view as part of the fun in cycling. If I lived in FL I’d be fine with the 48/35 like you mentioned, perhaps even the 46/33 